Posted By: The American Journal of Human Genetics, AJHG AJHG: What motivated you to start working on this project? AV: There’s a statistical genetic technique called Mendelian randomization, which can very easily identify if there is a causal link between two traits, as long as there are genome-wide association study (GWAS) summary statistics available for both of them.... Read More
The American Society of Human Genetics (ASHG) convened its Industry Roundtable in October 2025, bringing together leaders from ASHG and major companies in human genetics and genomics, including Illumina, PacBio, BridgeBio, and GeneDx. The Roundtable serves as a collaborative forum to discuss challenges and opportunities in the field, review progress on ongoing initiatives, and identify... Read More
Posted By: The American Journal of Human Genetics, AJHG AJHG: What motivated you to start working on this project? KZ: It was the growing tension between conclusions from controlled lab experiments and the immense variability in inherited disease I encountered during my clinical training. During my PhD, I used gene editing to neatly isolate the effect size of... Read More
Posted By: HGG Advances HGGA: What motivated you to start working on this project? Authors: Heart failure is common and deadly, but its genetics are hard to nail down because it’s highly polygenic, and many genome-wide association study signals haven’t been translated into actionable biology or treatment ideas. We were motivated by the strong genetic overlap between... Read More
As 2025 comes to a close, fiscal negotiations in Congress are intensifying, with significant implications for federal research budgets. Decisions on topline spending and appropriations will directly shape funding for agencies like the National Institutes of Health (NIH), the National Science Foundation (NSF), and the Advanced Research Projects Agency for Health (ARPA-H), influencing grant availability,... Read More