Publications & News

Autism is a neurodevelopmental condition affecting approximately 1 in 31 children (3.2%) and approximately 2.2% of adults.[1],[2] Research shows that genetic factors significantly contribute to autism; hundreds of genes and chromosomal variations are known to increase the likelihood of autism.[3] Advances in genetic testing – such as genome sequencing – and large-scale collaborative genomic studies... Read More

Posted By: The American Journal of Human Genetics, AJHG AJHG: What motivated you to start working on this project? XS: Alzheimer’s disease risk differs across populations, but much of the genetic and transcriptomic work in the field has historically focused on cohorts of European ancestry. That makes it harder to determine which disease-associated regulatory mechanisms are shared across... Read More

For Immediate Release: Wednesday, June 3, 10:00 a.m. U.S. Eastern Time Media Contact: Evelyn Mantegani, [email protected] Rockville, MD – The American Society of Human Genetics (ASHG) is pleased to announce the appointment of Charles Lee, PhD, DSc, FACMG, FRSC, as the new Editor-in-Chief of Human Genetics and Genomics Advances (HGG Advances), ASHG’s fully open-access journal. Dr. Lee will... Read More

Posted By: HGG Advances HGGA: What motivated you to start working on this project? AT: With my PhD training in statistical genetics and genomics, I was eager to complement my discovery-focused training with functional genomics approaches during my postdoc. During this stage of my training, I’ve focused on using massively parallel reporter assays (MPRAs), which are used to measure... Read More

Posted By: HGG Advances HGGA: What motivated you to start working on this project? HC: This project came out of an ongoing collaboration with Wendy K. Chung, MD, PhD. We have been working together on a series of neurodevelopmental disease genes—her team handles patient ascertainment and genomic analysis, and our lab contributes Drosophila-based functional genomics. MARK2 was... Read More