Each month, the editors of The American Journal of Human Genetics interview an author of a recently published paper. This month, we check in with Casey Romanoski to discuss her paper, “Systems Genetics in Human Endothelial Cells Identifies Non-coding Variants Modifying Enhancers, Expression, and Complex Disease Traits”. AJHG: What caused you to start working on... Read More
In March, ASHG hosted a webinar to share recent findings in the population genetics of ancient humans and to explore how genetic variation may have shaped early human history. This webinar, entitled, “New Insights into Ancient Genomes” featured ASHG members David Reich, PhD and Joshua Akey, PhD. During the session, they discussed methods for isolating... Read More
Author: Iris Nira Smith, PhD Postdoctoral Fellow Genomic Medicine Institute Lerner Research Institute Cleveland Clinic Smith IN, et al. Conformational dynamics and allosteric regulation landscapes of germline PTEN mutations associated with autism compared to those associated with cancer. 2019 American Journal of Human Genetics. May 2;104(5):861-878\ Why do mutations in the same gene sometimes lead... Read More