Posted By: The American Journal of Human Genetics, AJHG AJHG: What motivated you to start working on this project? AM: During my undergraduate studies in Colombia, I started working on rare diseases, and we often found several patients carrying the exact same genetic variant. Several populations have experienced founder events, such as Quebec and Colombia.... Read More
Posted By: The American Journal of Human Genetics, AJHG AJHG: What motivated you to start working on this project? ST: Previously, we proposed a haplotype-based scan for recent selection and validated the results in real data using known selected loci in European ancestry groups. We aimed to broaden our scope to more ancestry groups that are often underrepresented in human genetics studies. This objective required us to... Read More
Posted By: The American Journal of Human Genetics, AJHG AJHG: What motivated you to start working on this project? JD: As I began my PhD in statistical genetics, I wanted to start from the ground up. Much of the excitement in our field today centers on precision medicine, which utilizes genetics to refine disease risk prediction, identify novel... Read More
Posted By: The American Journal of Human Genetics, AJHG AJHG: What motivated you to start working on this project? Valerie Arboleda (VA): The most enjoyable projects often emerge from learning new methods and tackling shared problems. In this case, my friend, co-author (Keriann M. Backus, PhD), and lab neighbor had been generating exciting chemoproteomic datasets... Read More
Posted By: The American Journal of Human Genetics, AJHG AJHG: What motivated you to start working on this project? LB: A few years ago, I had an experience that made me realize that clinical genetic testing in the electronic health record (EHR) represented an enormous and largely untapped resource that could help patients and drive... Read More