Posted By: The American Journal of Human Genetics, AJHG AJHG: What motivated you to start working on this project? KZ: It was the growing tension between conclusions from controlled lab experiments and the immense variability in inherited disease I encountered during my clinical training. During my PhD, I used gene editing to neatly isolate the effect size of... Read More
Posted By: The American Journal of Human Genetics, AJHG AJHG: What motivated you to start working on this project? AM: During my undergraduate studies in Colombia, I started working on rare diseases, and we often found several patients carrying the exact same genetic variant. Several populations have experienced founder events, such as Quebec and Colombia.... Read More
Posted By: The American Journal of Human Genetics, AJHG AJHG: What motivated you to start working on this project? ST: Previously, we proposed a haplotype-based scan for recent selection and validated the results in real data using known selected loci in European ancestry groups. We aimed to broaden our scope to more ancestry groups that are often underrepresented in human genetics studies. This objective required us to... Read More
For Immediate Release: Tuesday, October 14, 2025, 11:00 a.m. U.S. Eastern Time Media Contact: Evelyn Mantegani, 202-725-2730, press@ashg.org Each year, editors of The American Journal of Human Genetics (AJHG) and Human Genetics and Genomics Advances (HGG Advances) recognize trainees and early career investigators for outstanding scientific contributions to the field of human genetics and genomics. We’re... Read More
Posted By: The American Journal of Human Genetics, AJHG AJHG: What motivated you to start working on this project? JD: As I began my PhD in statistical genetics, I wanted to start from the ground up. Much of the excitement in our field today centers on precision medicine, which utilizes genetics to refine disease risk prediction, identify novel... Read More