INVITED AND SPECIAL SESSIONS
Thursday, October 27
2:00 PM-4:30 PM
Concurrent Platform Sessions II (33-39) Click on abstract number to view full text
SESSION 34 - Unravelling Gordian Knots: Solutions to Complex Diseases
Hall 1
Co-Moderators: Lon Cardon, University of Oxford, UK; and Steve Warren, Emory University School of Medicine, Atlanta, GA
87/2:00 Case-control linkage disequilibrium difference (CCOLDD): a linkage disequilibrium mapping method in genome-wide association studies. M. G. Hayes and N. J. Cox.
88/2:15 Combined analysis of 4500 Single Nucleotide Polymorphisms from chromosome 1q21-25 in samples from eight linked populations reveals shared type 2 diabetes susceptibility variants. M. I. McCarthy, E. Zeggini, W. Rayner, C. J. Groves, B. D. Mitchell, J. O'Connell, S. C. Elbein, R. Hanson, L. J. Baier, W. C. Knowler, P. Froguel, W. P. Jia, M. C. Ng, J. C. Chan, L. R. Cardon, K. Xiang, C. Bogardus, S. E. Hunt, P. Deloukas, A. R. Shuldiner and International Type 2 Diabetes 1q Consortium.
89/2:30 Combining multiple susceptibility polymorphisms can increase the predictive power of genetic information: a study of replicated type 2 diabetes variants. A. T. Hattersley, M. N. Weedon, M. I. McCarthy, M. Walker, G. Hitman, B. Shields, K. R. Owen and T. M. Frayling.
90/2:45 The effects of genetic variation in PSARL on diabetes risk. J. Curran, J. Jowett, K. Elliott, L. Kerr-Bayles, S. Wanyoni, J. Skelton, K. H. Kim, T. Dyer, K. Walder, G. Collier, P. Zimmet, J. Blangero and A. Kissebah.
91/3:00 Population genetics of the metabolic syndrome. A. Di Rienzo, V. J. Clark, Y. Qian and R. R. Hudson.
92/3:15 Genome-wide haplotype signatures of hypertension with and without metabolic syndrome. P. Hamet, O. Seda, E. Merlo, J. Tremblay, U. Broeckel, D. Gaudet, G. Bouchard, F. Gagnon, G. Antoniol, P. L. Brunelle, A. Gurau, F. Gossard, J. Pintos, T. A. Kotchen, Z. Pausova, S. N. Orlov, R. Wan, M. Labuda, M. Jomphe and A. W. Cowley.
93/3:30 The RET Gene is a modifier of the PHOX2B gene for the Hirschprung disease phenotype. L. de Pontual, A. Pelet, D. Trochet, Y. Espinosa-Parrilla, A. Munnich, F. Jaubert, J. Feingold, S. Lyonnet and J. Amiel.
94/3:45 Differential liabilities of coding and non-coding mutations in complex disease. G. Burzynski, J. Amiel, G. Antinolo, S. Borrego, I. Ceccherini, E. Emison, C. Eng, R. Fernandez, M. Garcia-Barcelo, P. Griseri, R. Hofstra, C. Kashuk, F. Lantieri, S. Lyonnet, P. Tam, A. Tullio-Pelet, K. West and A. Chakravarti.
95/4:00 A dense genome SNP scan identifies a common determinant of obesity. A. Herbert, N. P. Gerry, M. McQueen, I. Heid, A. Pfeufer, T. Illig, H.-E. Wichmann, T. Meitinger, X. Zhu, R. Cooper, K. Ardlie, H. N. Lyons, J. N. Hirschhorn, N. M. Laird, M. E. Lenburg, C. Lange and M. F. Christman.
96/4:15 A Network Approach to Genetic Studies of Complex diseases. X. Zhou, F. Arnett and M. Xiong.