Page 104 - ASHG 2013 Program Guide

INVITED AND PLATFORM SESSIONS  
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INVITED AND PLATFORM SESSIONS
Thursday, October 24
8:00
AM
–10:15
AM
Concurrent Platform (abstract-driven)
Session B (19-27)
SESSION 22 – Cardiovascular Genetics: Gene
Discovery through GWAS and Sequencing
Room 210, Level 2, Convention Center
Moderators
:
Paul W. Livermore Auer, Univ. of
­
Wisconsin- Milwaukee; Leslie Lange, Univ. of North
Carolina at Chapel Hill
115
/8:00
Linkage analysis of hypertriglyceridemia
in a single large family identifies 3 novel potentially
pathogenic variants.
E. A. Rosenthal, J. Ranchalis,
J. D. Brunzell, A. G. Motulsky, D. A. Nickerson, E. M.
Wijsman, G. P. Jarvik.
116
/8:15
Rare
APOC3
loss-of-function variants
lower plasma triglycerides and protect against
clinical coronary heart disease.
J. Crosby, G.
M. Peloso, P. Auer, D. R. Crosslin, G. Jarvik, L. A.
Cupples, A. Reiner, E. Boerwinkle, S. Kathiresan, on
behalf of Exome Sequencing Project HDL/TG Working
Group.
117
/8:30
Novel rare and low frequency coding
variants associated with LDL cholesterol levels.
C. Willer, L. A. Lange, Y. Hu, H. Zhang, C. Xue, E.
M. Schmidt, M. Boehnke, L. Groop, M. McCarthy, T.
Meitinger, M. Fornage, C. Ballantyne, E. Boerwinkle,
D. Altshuler, D.-y. Lin, G. Jarvik, L. A. Cupples, C.
Kooperberg, J. G. Wilson, D. A. Nickerson, G. R.
Abecasis, S. S. Rich, R. P. Tracy, NHLBI Exome
Sequencing Project.
118
/8:45
Association analysis of C-reactive
protein levels in European Americans and African
Americans sequenced through the NHLBI Exome-
Sequencing Project.
U. M. Schick, P. L. Auer, D. S.
Kim, E. J. Benjamin, J. C. Bis, E. Boerwinkle, C. S.
Carlson, J. Dupuis, M. Fornage, L. Hsu, R. D. Jackson,
C. Kooperberg, L. Lange, H. Lin, S. M. Leal, A. C.
Morrison, N. Pankratz, U. Peters, B. Psaty, S. S. Rich,
R. Tracy, J. G. Wilson, M. D. Gross, A. P. Reiner, on
behalf of NHLBI GO Exome Sequencing Project.
119
/9:00
Genetic association studies illuminate
the role of low frequency and rare variation in
explaining the variation of blood pressure traits.
A. Manning, X. Sim, H. M. Highland, M. A. Rivas,
H. K. Im, A. Mahajan, A. E. Locke, N. Grarup, P.
Fontanillas, A. P. Morris, T. M. Teslovich, J. Flannick,
C. Fuchsberger, K. Gaulton, H. M. Kang, J. B. Meigs,
C. M. Lindgren, for T2D-GENES and GoT2D.
120
/9:15
Contribution of coding variation to type
2
diabetes-related quantitative traits in 13,000
exomes from multiple ancestries.
X. Sim, H. M.
Highland, M. A. Rivas, H. K. Im, A. K. Manning, A.
Mahajan, A. E. Locke, N. Grarup, P. Fontanillas, A. P.
Morris, T. M. Teslovich, J. Flannick, C. Fuchsberger,
K. Gaulton, H. M. Kang, J. B. Meigs, C. M. Lindgren,
T2D-GENES and GoT2D Consortia.
121
/9:30
A meta-analysis of genome-wide
association studies identifies a novel locus
associated with thrombin generation potential.
A. Rocañín-Arjó, L. Carcaillon, W. Cohen, N. Saut,
M. Germain, L. Letenneur, M. Alhenc-Gelas, A. M.
Dupuy, M. Bertrand, P. Amouyel, P. Y. Scarabin, D. A.
Trégouët, P. E. Morange.
122
/9:45
Genome-wide association analysis of
blood pressure traits in nearly 30,000 African
ancestry individuals reveals a common set of
associated genes in African and non-African
populations.
N. Franceschini, E. Fox, Z. Zhang,
T. Edwards, M. Nalls, Y. Sung, B. Tayo, Y. Sun, O.
Gottesman, A. Adeyemo, A. Johnson, J. Young, K.
Rice, H. Tang, J. Smith, G. Ehret, A. Morrison, E.
Boerwinkle, B. Psaty, D. Arnett, S. Redline, R. Cooper,
N. Risch, D. Rao, J. Rotter, A. Chakravarti, A. Reiner,
D. Levy, B. Keating, X. Zhu, AGEN Consortium.
123
/10:00
Gene pathway burden test application
to cardiovascular disease using whole genome
sequencing data.
M. A. A. Almeida, J. P. Peralta, J.
W. Kent, T. M. Teslovich, G. Jun, C. Fuchsberger, A.
R. Wood, A. Manning, T. M. Frayling, P. Cingolani, D.
M. Lehman, T. D. Dyer, G. Abecasis, L. Almasy, R.
Duggirala, J. Blangero.