Page 87 - ASHG 2012 Annual Meeting Program Guide

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INVITED AND PLATFORM SESSIONS
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SESSION 15 – New Loci for Obesity, Diabetes, and
Related Traits
Gateway Ballroom 104, Lower Level South, Moscone
Center
Moderators
:
Jose Florez, Massachusetts Gen. Hosp.;
Richa Saxena, Massachusetts Gen. Hosp.
43
/10:30
A genome-wide association analysis of
early-onset severe obesity: The SCOOP project.
E. Wheeler, N. Huang, E. Bochukova, S. Lindsay, J.
Keogh, R. J. F. Loos, N. J. Wareham, S. O’Rahilly, M.
Hurles, I. Barroso, I. S. Farooqi.
44
/10:45
Mapping obesity traits using an integrated
`omics’ approach in adipose tissue from female
twins.
A. K. Hedman, J. K. Sandling, E. Grundberg, K.
S. Small, E. Meduri, S. Keildson, A. Nica, A. Buil, J. T.
Bell, J. Nisbet, M. Sekowska, A. Wilk, A. Barrett, N.
Hassanali, T.-P. Yang, D. Glass, S.-Y. Shin, L. Parts, N.
Soranzo, R. Durbin, K. Ahmadi, K. T. Zondervan, C. M.
Lindgren, T. D. Spector, E. T. Dermitzakis, M. I.
McCarthy, P. Deloukas for MuTHER Consortium.
45
/11:00
Whole exome sequencing identifies
candidate causal genes for severe insulin
resistance.
F. Payne, A. Daly, W. Bottomley, E. Raffan,
E. Goncalves Serra, A. Thompson, D. B. Savage, R. K.
Semple, S. O’Rahilly, I. Barroso, UK10K Consortium.
46
/11:15
Exome analysis in 8,232 Finnish men
identifies novel loci and low-frequency variants for
insulin processing and secretion.
J. R. Huyghe, A.
U. Jackson, M. P. Fogarty, A. Stanáková, H. M.
Stringham, M. L. Buchkovich, C. Fuchsberger, J.
Paananen, P. S. Chines, T. M. Teslovich, J. M. Romm,
H. Ling, I. McMullen, R. Ingersoll, E. W. Pugh, K. F.
Doheny, J. Kuusisto, L. J. Scott, F. S. Collins, G. R.
Abecasis, R. M. Watanabe, M. Boehnke, M. Laakso, K.
L. Mohlke.
47
/11:30
Global genomic and transcriptomic
variation in human pancreatic islets reveals novel
loci associated with type 2 diabetes and related
traits.
J. Fadista, P. Vikman, I. Mollet, E. O. Laakso, U.
Krus, O. Hansson, L. Groop.
48
/11:45
Identification of a novel genome-wide
significant association with type 2 diabetes risk in
Mexicans and Mexican Americans.
A. L. Williams, H.
García-Ortiz, M. J. Gómez-Vázquez, C. A. Haiman, A.
Huerta-Chagoya, A. K. Manning, C. Márquez-Luna, H.
Moreno-Macías for SIGMA Type 2 Diabetes
Consortium.
49
/12:00
Discovery and fine-mapping of type 2
diabetes susceptibility loci through trans-ethnic
meta-analysis.
A. Mahajan, J. E. Below, W. Zhang, M.
J. Go, E. Parra, A. P. Morris, AGEN-T2D, DIAGRAM,
MA-T2D and SA-T2D Consortia.
50
/12:15
TCF7L2
genetic variation is associated
with impaired incretin effect and lower glucagon.
B.
Chamarthi, K. R. Littleton, V. Kaur, L. Chen, A. K.
Manning, M. K. Thomas, M. S. Hudson, J. C. Florez.
51
/12:30
Novel locus including
FGF21
is associated
with dietary macronutrient intake.
A. Y. Chu, T.
Workalemahu, N. P. Paynter, L. M. Rose, F. Giulianini,
CHARGE Nutrition Working Group, Q. Qi, G. C.
Curhan, E. B. Rimm, D. J. Hunter, L. R. Pasquale, P.
M. Ridker, F. B. Hu, D. I. Chasman, L. Qi on behalf of
DietGen Consortium.
Wednesday, November 7
10:30
AM
–12:45
PM
Concurrent Platform (abstract-driven)
Session A (11-19)