Page 114 - ASHG 2012 Annual Meeting Program Guide

INVITED AND PLATFORM SESSIONS
103
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INVITED AND PLATFORM SESSIONS
Friday, November 9
8:00
AM
–10:15
AM
Concurrent Platform (abstract-driven)
Session D (47-55)
SESSION 50 – Population Genetics Genome-Wide
Room 134, Lower Level North, Moscone Center
Moderators
:
Melissa A. Wilson Sayres, Univ. of
California, Berkeley; Sarah Tishkoff, Univ. of
Pennsylvania
277
/8:00
Direct measure of human somatic base-
substitution mutation rate in monozygotic twins.
J. B. Richards, R. Li, A. Montpetit, T. D. Spector, C.
Polychronakos.
278
/8:15
Estimating human mutation rate using
autozygosity in a founder population.
C. D.
Campbell, J. X. Chong, M. Malig, A. Ko, B. L. Dumont,
L. Han, L. Vives, B. J. O’Roak, P. H. Sudmant,
M. Abney, C. Ober, E. E. Eichler.
279
/8:30
The myth of random mating: Evidence
of ancestry-related assortative mating across 3
generations in Framingham, MA.
R. Sebro, G.
Peloso, J. Dupuis, N. Risch.
280
/8:45
Combined analysis of loss-of-function
variants in protein-coding genes from over 16,000
individuals.
D. G. MacArthur, M. Lek, K. Shakir, S.
Balasubramanian, E. Lim, B. M. Neale, L. Habegger,
S. Gabriel, P. Sullivan, S. Kathiresan, M. I. McCarthy,
M. Boehnke, S. Purcell, S. A. McCarroll, M. B. Gerstein,
D. Altshuler, M. A. DePristo, M. J. Daly.
281
/9:00
Abundant selection explains low diversity
on human Y chromosomes.
M. Wilson Sayres, K.
Lohmueller, R. Nielsen.
282
/9:15
The genomic geography of close relatives
across Europe.
P. Ralph, G. Coop.
283
/9:30
Evolutionary history and adaptation
inferred from whole-genome sequences of diverse
African hunter-gatherers.
J. Lachance, B. Vernot,
C. Elbers, B. Ferwerda, A. Froment, J. Bodo, G. Lema,
W. Fu, T. Nyambo, T. Rebbeck, K. Zhang, J. Akey,
S. Tishkoff.
284
/9:45
Mapping the human genome’s missing
pieces using population admixture.
G. Genovese,
R. E. Handsaker, H. Li, N. Altemose, A. M. Lindgren,
K. Chambert, B. Pasaniuc, A. Price, D. Reich, C. C.
Morton, M. R. Pollak, J. G. Wilson, S. A. McCarroll.
285
/10:00
When ancestry runs deep: Trans-species
polymorphisms in apes.
L. Segurel, E. Leffler, Z. Gao,
S. Pfeifer, A. Auton, O. Venn, L. Stevison, A. Venkat,
J. L. Kelley, J. Kidd, C. Bustamante, R. Bontrop, M.
Hammer, J. Wall, P. Donnelly, G. McVean,
M. Przeworski.
Friday, November 9
8:00
AM
–10:15
AM
Concurrent Platform (abstract-driven)
Session D (47-55)
SESSION 51 – Endless Forms Most Beautiful: Variant
Discovery in Genomic Data
Gateway Ballroom 104, Lower Level South, Moscone
Center
Moderators
:
Terry Furey, Univ. of North Carolina at
Chapel Hill; Deanna Church, NCBI/NIH
286
/8:00
Dark matter of the diseasome: Annotating
personal genomes for gene regulatory disease risk
alleles.
G. Bejerano.
287
/8:15
Causal mutation discovery using next-
generation sequencing data: Development and
application of a pipeline to reduce false positive
calls and to map regions of shared homozygosity
and IBD.
S. Gulsuner, T. Walsh, A. C. Watts, M. K. Lee,
T. Ozcelik, M. C. King.
288
/8:30
A new framework for large-scale genomic
variant discovery and validation using pooled
sequencing data.
G. del Angel, M. Carneiro, E. Banks,
R. Poplin, C. Hartl, M. A. DePristo.
289
/8:45
Discovery of genomic variants from RNA-
sequencing data.
R. Piskol, G. Ramaswami, J. B. Li.
290
/9:00
zCall: A rare variant caller for array-based
genotyping.
J. I. Goldstein, A. Crenshaw, J. Carey, G.
Grant, J. Maguire, M. Fromer, C. O’Dushlaine, J. L.
Moran, K. Chambert, C. Stevens, P. Sklar, C. Hultman,
S. Purcell, S. McCarroll, P. F. Sullivan, M. J. Daly, B.
M. Neale, Swedish Schizophrenia Consortium, ARRA
Autism Sequencing Consortium.
291
/9:15
Copy number detection and variant
classification in the DDD project.
T. W. Fitzgerald,
K. I. Morley, M. van Kogelenberg, E. Bragin,
P. Vijayarangakannan, A. Tivey, S. Clayton, S. Gribble,
C. Wright, D. FitzPatrick, H. Firth, J. Barrett, N. Carter,
M. Hurles.
292
/9:30
Removal of mapping biases in sequence-
based functional data improves regulatory element
identification at heterozygous variants.
M. Buchkovich, K. L. Mohlke, T. S. Furey.
293
/9:45
SNP discovery in diverse human
populations by rapid, very-low-cost next-generation
sequencing of reduced representation libraries.
T. F. Cooke, M. C. Yee, M. Muzzio, R. Bell,
O. E. Cornejo, C. D. Bustamante, E. E. Kenny.
294
/10:00
HIBAG -- HLA genotype imputation with
attribute bagging.
X. Zheng, J. Shen, C. Cox,
J. Wakefield, M. Ehm, M. Nelson, B. Weir.