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Wednesday, October 12
4:15
PM
–6:15
PM
Concurrent Platform Session A (10-19)
SESSION 19 – Cardiovascular Genetics I: Complex
Traits
Room 510, Level 5, Convention Center
Moderators:
Stuart Macgregor, Queenland Inst. Med.
Res., Australia; Joanne Curran, Texas Biomed. Res.
Inst., USA
75
/4:15
Multiple novel loci conferring risk to
coronary artery disease identified in a study of
63,253 cases and 126,820 controls.
S. Kanoni, C.
Willenborg, J. Thompson, K. Stirrups, C. Nelson, J.
Danesh, J. Erdmann, A. Hamsten, S. Kathiresan, J. S.
Kooner, R. Roberts, U. Thorsteinsdottir, H. Watkins, H.
Schunkert, N. Samani, P. Deloukas for the
CARDIoGRAMplusC4D Consortium.
76
/4:30
Twenty-nine common variants associated
with blood pressure and cardiovascular disease
risk: The International Consortium for Blood
Pressure Genome-Wide Association Studies.
G. B.
Ehret, P. B. Munroe, K. M. Rice, M. Bochud, A. D.
Johnson, D. I. Chasman, A. V. Smith, M. D. Tobin, G.
C. Verwoert, V. Pihur, N. R. G. Shrine, L. V. Wain, M.
Boehnke, M. G. Larson, M.-R. Järvelin, B. M. Psaty, G.
R. Abecasis, A. Chakravarti, P. Elliott, C. M. van Duijn,
C. Newton-Cheh, D. Levy, M. J. Caulfield, T. Johnson
on behalf of ICBP-GWAS Consortium.
77
/4:45
A large-scale genome-wide association
study of PR interval identifies 41 loci associated
with atrial and atrioventricular conduction.
A.
Isaacs, J. van Setten, D. E. Arking, E. J. Rossin, D. S.
Evans, V. Gudnason, C. Hayward, A. A. Hicks, Y.
Jamshidi, K. Kerr, B. Krijthe, T. Lehtimäki, M. Müller, S.
Padmanabhan, A. Parsa, O. Polasek, R. B. Schnabel,
K. Stefansson, T. Tanaka, A. Teumer, K. Tarasov, S.
Trompet, S. Ulivi, Vanderbilt Genomic Electronic
Records, P. van der Harst, X. Yin, P. I. W. de Bakker,
N. Sotoodehnia on behalf of PRIMA Consortium.
78
/5:00
Association meta-analysis of correlated
EKG traits detect novel loci that influence
electrically active left ventricular cardiac mass.
J.
van Setten, A. Isaacs, D. E. Arking, J. C. Chambers,
M. Eijgelsheim, C. Hayward, S. Hwang, Y. Jamshidi, K.
Kerr, T. Lehtimäki, I. Mateo Leach, M. Mueller, O.
Meirelles, A. Pfeufer, O. Polasek, N. J. Samani, A. V.
Smith, R. Sorice, N. Sotoodehnia, T. Tanaka, A.
Teumer, S. Trompet, S. Ulivi, P. I. W. de Bakker, P. van
der Harst on behalf of QRS Voltage Consortium.
79
/5:15
Metabonomic and genetic fine mapping
reveal wide range of associations across
metabolites in known lipid loci.
T. Tukiainen, J.
Kettunen, A. J. Kangas, L.-P. Lyytikäinen, P. Soininen,
A.-P. Sarin, E. Tikkanen, P. F. O’Reilly, M. J.
Savolainen, K. Kaski, A. Jula, T. Lehtimäki, M.
Kähönen, J. Viikari, M. Jauhiainen, J. G. Eriksson, O.
Raitakari, V. Salomaa, M.-R. Järvelin, M. Perola, A.
Palotie, M. Ala-Korpela, S. Ripatti.
Cameras and all other recording devices are
strictly prohibited
in all session rooms. Thank you for your cooperati
80
/5:30
Meta-analysis of Metabochip SNPs
identifies novel waist-hip ratio loci involved in
adipogenesis and chronic inflammation disorders
D. C. Croteau-Chonka, T. Ferreira, D. Shungin, T. W.
Winkler, R. Magi, R. J. Strawbridge, A. E. Locke, K.
Fischer, T. Workalemahu, P. J. Griffin, C. C. White, A
U. Jackson, F. Day, M. C. Zillikens, I. Barroso, C. S.
Fox, E. Ingelsson, M. I. McCarthy, K. E. North, E. K.
Speliotes, P. W. Franks, L. A. Cupples, L. Qi, I. M.
Heid, K. L. Mohlke, C. M. Lindgren, R. J. F. Loos,
Genetic Investigation of Anthropometric Traits
Consortium.
81
/5:45
A human hormone sensitive lipase
knockout: Window into mechanisms of
dyslipidemia and diabetes.
J. Albert, R. Horenstein
L. Yerges-Armstrong, U. Sreenivasan, S. Snitker, J.
O’Connell, J. McLenithan, A. Shuldiner, C. Sztalryd,
Damcott.
82
/6:00
The 9p21.3 coronary artery disease risk
genotype is associated with elevated serum level
of interferon alpha 21.
N. A. M. Almontashiri, M. Fa
H. H. Chen, A. C. T. Teng, B. L. M. Cheng, R.
McPherson, R. Roberts, A. F. R. Stewart.